Label Review Training: Module 3: Special Issues, Page 27

Section 6: How should I review worker protection labeling?

Determining Restricted Entry Intervals

The correct REI may be specified in the regulatory assessment document. If a regulatory assessment document is not available, refer to Supplement Three-A of Pesticide Registration (PR) Notice 93-7, or use the following guidance to determine the correct REI.

To determine REIs, follow the steps below, but be sure to also check any RED or registration review documents to determine if a specific REI was set on a case-by-case basis for this chemical.

Step 1: Identify acute toxicity data to be used in determining REIs

REIs are based on the most severe acute toxicity category assigned to the acute dermal, eye irritation, and skin irritation data for all of the active ingredients in a product. In many instances, these data are not always available. Refer to Chapter 10, Section VII.C of the Label Review Manual for a list indicating the preferred order for selecting data with which to determine the toxicity category for each active ingredient.

Step 2: Determine appropriate REI(s) using the chart below

Resource

For more information about REIs, see Chapter 10, Section VIII of the Label Review Manual or Supplement Three-A of PR Notice 93-7.

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