Reduced Risk and Organophosphate Alternative Decisions for Conventional Pesticides
Updated May 2024
Reduced risk pesticides are described in the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA section 3(c)(10)), which establishes an expedited review for applications for registration and amendments to registrations for pesticides that "may reasonably be expected to accomplish one or more of the following:
- Reduce the risks of pesticides to human health.
- Reduce the risks of pesticides to nontarget organisms.
- Reduce the potential for contamination of groundwater, surface water or other valued environmental resources.
- Broaden the adoption of integrated pest management strategies, or make such strategies more available or more effective."
Pesticide Registration Notice 97-3, Guidelines for Expedited Review of Conventional Pesticides under the Reduced-Risk Initiative and for Biological Pesticides, describes the review process and lists characteristics of acceptable and unacceptable submissions for the reduced-risk initiative.
OP alternative status is described in PR Notice 98-7, Changes to Registration Priority System Involving OP Alternatives and Reduced-Risk Candidates. OP alternative status was not considered by the Reduced Risk Program for conventional pesticides until FY 1999.
Information about the Table Contents
Pesticide Type
- F= fungicide,
- H= herbicide,
- I= insecticide,
- PGR= plant growth regulator,
- Re= repellent,
- Ro= rodenticide
Reduced Risk/OP alternative:
- RR=reduced risk,
- OP Alt.=organophosphate alternative
New active ingredient reduced risk/OP alternative actions are indicated by italics in the "Chemical" column.
| Registrant | Pesticide Type | Chemical | Site | Reduced Risk OP Alt | Registration Date* | Completion FY |
|---|---|---|---|---|---|---|
| IR-4 | I | Etoxazole | Sweet corn | RR | October 30, 2018 | 2019 |
| IR-4 | I | Flonicamid | Legume, Crop Group 6 (except soybean) and greenhouse grown pepper | RR | July 7, 2017 | 2017 |
| Syngenta | F | Pydiflumetofen | Berries, low growing crop Subgroup 13-07G (except cranberry and blueberry), Brassica Leafy Greens Subgroup 4-16B, Bushberry Crop Subgroup 13-07B, Citrus Crop Subgroup 10-10, Cottonseed Subgroup 2C, Edible-podded Legume Vegetables Subgroup 6A, Succulent Shelled Pea and Bean Subgroup 6B, Tree Nuts Crop Group 14-12, Canola, cereal grains, corn, cucurbit vegetables, fruiting vegetables, grape, leafy vegetables, peanut, dried shelled pea and bean, potato, soybean, golf course turf, and ornamentals | RR | August 30, 2019 | 2019 |
| DuPont Crop Protection | I | Cyantraniliprole | Berries Subgroup 13-07H, Soybeans | RR | November 13, 2018 | 2019 |
| ISK Biosciences Corp | I | Cyclaniliprole | Ornamentals, Conifers, Christmas trees and non-bearing fruit, Nut and vines grown in greenhouses, shades houses, and nurseries | RR | April 18, 2019 | 2019 |
| ISK Biosciences Corp | I | Cyclaniliprole | Citrus, tuberous and corm vegetables, Berries, and Small fruit | RR | September 20, 2019 | 2019 |
| IR-4 | I | Fenpyroximate | Leaf petiole vegetable Subgroup 22B, Bushberry Subgroup 13-07B, Squash/cucumber Subgroup 9B, and succulent bean | RR | December 12, 2019 | 2020 |
| IR-4 | I | Flonicamid | Oilseed Subgroup 20B Sunflower Subgroup | RR | April 8, 2019 | 2019 |
| DuPont Crop Protection | I | Indoxacarb | Corn | RR | May 28, 2020 | 2020 |
| IR-4 | I | Etoxazole | Sugar Beet (Crop Group 2 Leaves of Root and tuber Vegetables Subgroup, 1A Root Vegetables) | RR | January 6, 2020 | 2020 |
| OAT Agrio Co., Ltd. | F | Flutianil | Apple, Cantaloupe, Cherry, Cucumber, Grape, Squash, and Strawberry | RR | January 30, 2020 | 2020 |
| DuPont Crop Protection | I | Fluazaindolizine | Carrots, Cucurbit Vegetables (Crop Group 9), Fruiting Vegetables (Crop Group 8-10), Tuberous and Corm Vegetables (Crop Group 1C), Nonbearing Citrus Fruits, Stone Fruits, Tree Nuts and Vine Climbing Small Fruits (Groups 10-10, 12-12, 14-12 and 13-07F) | RR | September 6, 2023 | 2023 |
| ISK Biosciences Corp | I | Flonicamid | Ornamentals | RR | April 2, 2021 | 2021 |
| IR-4 | I | Flupyradifurone | Asparagus, Sesame, Sunflower/Safflower, Coffee, Pineapple, Grass, Dates, and Sweet Sorghum | RR | August 21, 2020 | 2020 |
| IR-4 | I | Acequinocyl | Banana | RR | August 31, 2021 | 2021 |
| BASF | F | Mefentrifluconazole | Carrots, cucurbits, and tomatoes. | RR | November 6, 2020 | 2021 |
| Syngenta | F | Picarbutrazox | Cotton, Legume (Crop Group 6), Barely, Buckwheat, Oats, Millet, Pearl, Rye, teosinte, triticale | RR | June 30, 2022 | 2022 |
| Nisso America, Inc. | F | Ipflufenoquin | Almond and Fruit, Pome, Group 11-10 | RR | March 29, 2022 | 2022 |
| Mitsui/Landis | F | Penthiopyrad | Banana, greenhouse grown lettuce | RR | 4/6/2023 | 2023 |
| Bayer CropScience | I | Flupyradifurone | Stone fruit, avocado, pomegranate, ornamentals, greenhouse vegetables | RR | 12/1/2015 | 2016 |
| ISK Biosciences Corporation | I | Cyclaniliprole | Pome fruit, stone fruit, tree nuts, grapes, fruiting vegetables, leafy vegetables, Brassica vegetables, cucurbit vegetables | RR | 1/12/2017 | 2017 |
| Dow | I | Hexaflumuron | below-ground bait station (termites) | RR | 3/10/1994 | 1994 |
| RJ Advantage | Re | Methyl Anthranilate | cherry, blueberry, grape, forestry | RR | 9/16/1994 | 1994 |
| Valent | H | Flumiclorac-pentyl | corn, soybean | RR | 11/18/1994 | 1995 |
| Rohm & Haas | I | Tebufenozide | walnut | RR | 5/15/1995 | 1995 |
| Sankyo | F | Hymexazol | sugar beet (seed treatment) | RR | 8/4/1995 | 1995 |
| Novartis | F | Fludioxonil | corn | RR | 10/5/1995 | 1996 |
| American Cyanamid | H | Imazapic | peanut | RR | 3/5/1996 | 1996 |
| Novartis | F | Mefenoxam | all metalaxyl uses | RR | 3/5/1996 | 1996 |
| Zeneca | F | Azoxystrobin | non-residential turf | RR | 2/7/1997 | 1997 |
| Dow | I | Spinosad | cotton | RR | 2/18/1997 | 1997 |
| Novartis | H | Alpha-metolachlor | all metolachlor uses | RR | 3/14/1997 | 1997 |
| American Cyanamid | H | Imazamox | soybean | RR | 5/23/1997 | 1997 |
| Dow | I | Hexaflumuron | above ground bait stations (termites) | RR | 5/21/1997 | 1997 |
| Zeneca | F | Azoxystrobin | grape, banana, peach, tomato, pecan, peanut | RR | 6/3/1997 | 1997 |
| Novartis | F | Fludioxonil | potato | RR | 10/10/1997 | 1998 |
| Novartis | F | Fludioxonil | seed treatments (brassica leafy veg., bulb veg., cereal grains, cotton, cucurbit veg., foliage of legume veg., fruiting veg., grass, herbs and spices, leafy veg., leaves and roots of tuber veg., legume veg., non-grass animal feeds, peanut, rape seed, root and tuber veg., sunflower) | RR | 10/10/1997 | 1998 |
| Ensystex | I | Diflubenzuron | below ground bait station (termite) | RR | 1/28/1998 | 1998 |
| Novartis | F | Cyprodinil | stone fruit | RR | 4/10/1998 | 1998 |
| Dow AgroSciences | I | Spinosad | almond, apple, citrus, brassica leafy veg., fruiting veg., leafy veg. | RR | 4/15/1998 | 1998 |
| Valent | I | Pyriproxyfen | cotton | RR | 6/18/1998 | 1998 |
| Rohm & Haas | I | Tebufenozide | pecan | RR | 6/1/1998 | 1998 |
| FMC | H | Carfentrazone-ethyl | wheat, corn | RR | 9/23/1998 | 1998 |
| Zeneca | F | Azoxystrobin | turf (residential) | RR | 10/1/1998 | 1999 |
| BASF | H | Diflufenzopyr | corn | RR | 1/28/1999 | 1999 |
| Zeneca | F | Azoxystrobin | almond, cucurbit veg, rice, wheat | RR | 3/17/1999 | 1999 |
| Zeneca | F | Azoxystrobin | canola, potato, stone fruit | RR | 3/17/1999 | 1999 |
| Rohm & Haas | I | Tebufenozide | leafy veg., brassica leafy veg, fruiting veg. | RR/OP Alt. | 4/14/1999 | 1999 |
| Valent | I | Pyriproxyfen | pome fruit, walnut | RR/OP Alt. | 4/14/1999 | 1999 |
| Monsanto | H | Glyphosate | glyphosate-tolerant corn, canola, sugar beet | RR | 4/14/1999 | 1999 |
| Rohm & Haas | I | Tebufenozide | cranberry | RR/OP Alt. | 4/20/1999 | 1999 |
| BASF | H | s-Dimethenamid | corn, soybean, peanut | RR | 5/10/1999 | 1999 |
| Dow AgroSciences | I | Spinosad | sweet corn | RR/OP Alt. | 5/26/1999 | 1999 |
| Bayer/Tomen | F | Fenhexamid | grape, strawberry, ornamentals | RR | 5/28/1999 | 1999 |
| Rohm & Haas | I | Tebufenozide | forestry, ornamentals | RR/OP Alt. | 6/16/1999 | 1999 |
| IR-4 | I | Tebufenozide | berry crop group, mint | RR/OP Alt. | 6/18/1999 | 1999 |
| Uniroyal | I | Bifenazate | ornamentals | RR/OP Alt. | 6/24/1999 | 1999 |
| Rohm & Haas | I | Tebufenozide | pome fruit, cotton | RR/OP Alt. | 7/21/1999 | 1999 |
| Rohm & Haas | I | Tebufenozide | sugarcane | RR/OP Alt. | 9/22/1999 | 1999 |
| Dow AgroSciences | I | Spinosad | cucurbit veg., stone fruit, legume veg, cereal grains | RR/OP Alt. | 9/23/1999 | 1999 |
| Novartis | F | Trifloxystrobin | pome fruit, grape, cucurbit veg., peanut, turf, banana, ornamentals | RR | 9/27/1999 | 1999 |
| Rhone-Poulenc | I | Fipronil | outside home use (termite) | OP Alt. | 9/28/1999 | 1999 |
| Novartis | I | Pymetrozine | tuberous and corm veg., ornamentals, tobacco | RR/OP Alt. | 9/29/1999 | 1999 |
| IR-4 | I | Tebufenozide | turnip, canola | RR | 9/29/1999 | 1999 |
| Valent | I | Pyriproxyfen | citrus, fruiting veg., tree nuts | RR/OP Alt. | 10/21/1999 | 2000 |
| Rohm & Haas | I | Tebufenozide | ornamentals (residential) | RR/OPAlt. | 11/12/1999 | 2000 |
| GMJA (Tropicana) | H/I/PGR | Ecolyst | orange | RR | 12/30/1999 | 2000 |
| Elanco | I | Spinosad | non-grass animal feed crop group, grain amaranth, cilantro, grass, buckwheat, rye, pistachio, oat, barley, millet, apple, popcorn, ti leaves, watercress, tropical fruit, teosinte, turnip greens | RR/OP Alt. | 1/12/2000 | 2000 |
| Bayer/Tomen | F | Fenhexamid | almond, stone fruit | RR | 4/13/2000 | 2000 |
| BASF | H/PGR | Prohexadione calcium | apple | RR | 5/3/2000 | 2000 |
| Rohm & Haas | I | Tebufenozide | tree nuts | RR/OP Alt. | 5/10/2000 | 2000 |
| Rohm & Haas | I | Methoxyfenozide | cotton, pome fruit | RR/OP Alt. | 6/12/2000 | 2000 |
| Novartis | F | Trifloxystrobin | almond, fruiting veg., hops, potato, sugar beet, wheat, ornamentals | RR | 7/18/2000 | 2000 |
| FMC | H | Carfentrazone-ethyl | cereal grains | RR | 8/9/2000 | 2000 |
| Novartis | I | Pymetrozine | cucurbit veg, fruiting veg. | RR/OP Alt. | 8/9/2000 | 2000 |
| AgrEvo | I | Buprofezin | cucurbit veg., head lettuce | RR/OP Alt. | 8/31/2000 | 2000 |
| Nihon Nohyaku America, Inc | I | Fenpyroximate | ornamentals (greenhouse) | RR/OP Alt. | 9/29/2000 | 2000 |
| DuPont | I | Indoxacarb | cotton, fruiting veg., brassica leafy veg., lettuce, sweet corn, pome fruit | RR/OP Alt. | 9/29/2000 | 2000 |
| Corteva | H | Florpyrauxifen-benzyl | Rice, Aquatics | RR | 10/06/2017 | 2018 |
| Bayer | H | Flucarbazone-sodium | wheat | RR | 9/29/2000 | 2000 |
| IR-4 | H | Glyphosate | animal feed, non-grass group (exc. alfalfa); aloe vera; ambarella; artichoke, globe; bamboo shoots; betelnut; biriba; blimbe; borage, seed; buffalo gourd; chaya; crambe, seed; custard apple; dokudami; epazote; feijoa; flax; foliage of legume veg.; galangal root; ginger, white (flower); Governor’s plum; gow kee leaves; grass, forage, fodder and hay group; herb and spices group; hops; ilama; imbe; imbu; jojoba (seed); juneberry; kava (root); kenaf; leafy veg.; leaves of root and tuber veg.; lesquerella (seed); leucaena; lingonberry; meadowform (seed); mioga (flower); mustard seed; okra; oregano, Mexican (leaves); palm heart; palm oil; papaya, Mountain papaya; pawpaw; pepper leaf; perilla (tops); pulasan; quinoa grain; root and tuber veg.; salal; sesame seed; Spanish lime; stevia (leaves); surinam cherry; teff, grain; ti leaves; wasabi (roots); water spinach (tops); watercress, upland; wax jambu; yacon tuber | RR | 9/27/2000 | 2000 |
| Zeneca | F | Azoxystrobin | barley, onion, citrus, corn (field, sweet, pop), cotton, leafy veg, root and tuber veg., soybean | RR | 9/29/2000 | 2000 |
| Rhone Poulenc | I | Fipronil | home lawn, golf course, commercial and recreational turf and sod farms (fire ant) | OP Alt. | 12/4/2000 | 2001 |
| Rhone Poulenc | I | Fipronil | potting medium mixtures (fire ant) | OP Alt. | 12/8/2000 | 2001 |
| Novartis | I | Thiamethoxam | barley, canola, cotton, sorghum, wheat (all seed treatment) | OP Alt. | 12/21/2000 | 2001 |
| Novartis | F | Fludioxonil | strawberry, bulb vegetables | RR | 12/29/2000 | 2001 |
| MGK | I | Pyriproxyfen | food handling establishments | RR | 3/14/2001 | 2001 |
| Novartis | F | Fludioxonil | turf | RR | 3/30/2001 | 2001 |
| Bayer | I | Imidacloprid | leaf petioles, citrus | OP Alt. | 4/10/2001 | 2001 |
| Rhone Poulenc | F | Zoxamide | grape | RR | 4/11/2001 | 2001 |
| Novartis | I | Thiamethoxam | cotton (foliar), cucurbit veg., fruiting veg., pome fruit, tuberous and corm veg. | OP Alt. | 5/23/2001 | 2001 |
| Rhone Poulenc | I | Fipronil | turf (homeowner, commercial; fire ant) | OP Alt. | 5/25/2001 | 2001 |
| BASF | PGR | Prohexadione calcium | grass (grown for seed) | RR | 6/1/2001 | 2001 |
| Valent/IR-4 | I | Pyriproxyfen | pistachio | RR/OP Alt. | 6/5/2001 | 2001 |
| Zeneca | H | Mesotrione | corn (field) | RR | 6/21/2001 | 2001 |
| Novartis | F | Cyprodinil | onion (dry bulb & green), strawberry | RR | 6/22/2001 | 2001 |
| AgrEvo | I | Buprofezin | almond, citrus, cotton, grape, tomato | RR/OP Alt. | 6/26/2001 | 2001 |
| FMC | H | Carfentrazone-ethyl | cotton (defoliant use) | OP Alt. | 8/1/2001 | 2001 |
| ISK | F | Fluazinam | peanut, potato | RR | 9/7/2001 | 2001 |
| FMC | I | zeta-Cypermethrin | alfalfa, corn (field, pop, sweet), head and stem brassica veg., leafy brassica greens, leafy veg., onion (green), sugar beet, sugarcane, rice | OP Alt. | 9/17/2001 | 2001 |
| Novartis | F | Azoxystrobin | leafy brassica greens, bushberry, eggplant, grass (grown for seed), jackfruit, juneberry, lingonberry, loquat, mint (spearmint, peppermint), okra, pawpaw, pepper, persimmon, salal, strawberry, tamarind, tropical fruit, turnip (greens), watercress, wax jambu, white sapote | RR | 9/21/2001 | 2001 |
| Makhteshim-Agan | I | Novaluron | ornamentals (indoors, non-food) | RR | 9/24/2001 | 2001 |
| Dow Elanco | I | Spinosad | artichoke (globe), asparagus, bushberry, cranberry, foliage of legume veg., garden beet (root), juneberry, leaves of root and tuber veg., lingonberry, okra, pistachio, pome fruit, salal, strawberry, sugar beet (root), tree nuts |
RR/OP Alt. | 9/25/2001 | 2001 |
| Rohm & Haas | F | Zoxamide | cucurbit veg., tomato | RR | 9/26/2001 | 2001 |
| PBI Gordon | H | Carfentrazone-ethyl | turf | RR | 9/27/2001 | 2001 |
| American Cyanamid | I | Chlorfenapyr | post construction control of termites | OP Alt. | 12/21/2001 | 2002 |
| American Cyanamid | H | Imazamox | alfalfa, canola, legume veg., wheat | RR | 12/27/2001 | 2002 |
| Novartis | I | Pymetrozine | cotton | RR/OP Alt. | 12/27/2001 | 2002 |
| Novartis | I | Pymetrozine | leafy veg., head and stem brassica veg., leafy brassica veg., hops | RR/OP Alt. | 12/27/2001 | 2002 |
| Novartis | I | Pymetrozine | pecans | OP Alt. | 12/27/2001 | 2002 |
| Uniroyal | I | Bifenazate | cotton, grape, hops, nectarine, peach, plum, pome fruit, strawberry | RR/OP Alt. | 2/1/2002 | 2002 |
| Aventis | I | Acetamiprid | cotton, pome fruit, citrus, grapes, brassica leafy veg., leafy veg. (excl. brassica), fruiting veg., ornamentals | RR/OP Alt. | 3/15/2002 | 2002 |
| Novartis | F | Trifloxystrobin | citrus, corn (field, pop), pecan, rice, stone fruit | RR | 5/23/2002 | 2002 |
| DowAgro | H | Cyhalofop-butyl | rice | RR | 5/23/2002 | 2002 |
| Dow | I | Indoxacarb | alfalfa, peanut, potato, soybean | RR/OP Alt. | 7/10/2002 | 2002 |
| Novartis | F | Fludioxonil | caneberry, pistachio, stone fruit, watercress | RR | 8/2/2002 | 2002 |
| Valent | I | Pyriproxyfen | stone fruit | RR/OP Alt. | 8/28/2002 | 2002 |
| IR-4 | Pyriproxyfen | blueberry, lychee, guava | RR/OP Alt. | 8/28/2002 | 2002 | |
| BASF/American Cyanamid | H | Imazethapyr | rice | RR | 8/29/2002 | 2002 |
| BASF/IR-4 | H | Diflufenzopyr (Distinct) | corn (pop, sweet), grass (forage, hay) | RR | 8/29/2002 | 2002 |
| Camas Tech. | F | Macalayea extract | greenhouse ornamentals | RR | 9/19/2002 | 2002 |
| Syngenta | F | Azoxystrobin | legume vegetables | RR | 9/20/2002 | 2002 |
| Rohm & Haas | I | Methoxyfenozide | fruiting vegetables, grapes | RR/OP Alt. | 9/20/2002 | 2002 |
| Rohm & Haas | I | Methoxyfenozide | brassica leafy vegetables, leafy vegetables | RR/OP Alt. | 9/20/2002 | 2002 |
| Rohm & Haas | I | Methoxyfenozide | corn (field, sweet) | RR/OP Alt. | 9/20/2002 | 2002 |
| Rohm & Haas | I | Methoxyfenozide | stone fruit | RR/OP Alt. | 9/20/2002 | 2002 |
| Rohm & Haas | I | Methoxyfenozide | tree nuts | RR/OP Alt. | 9/20/2002 | 2002 |
| Aventis | F | Fenamidone | lettuce | RR | 9/27/2002 | 2002 |
| Zeneca | I | Lambda-cyhalothrin | legume vegetables, fruiting vegetables, sugar cane |
RR OP Alt. (all uses) |
9/27/2002 | 2002 |
| IR-4 | I | Spinosad | berry group, fig, grape, herbs, peanut, root and tuber vegetables | RR/OP Alt. | 9/27/2002 | 2002 |
| Syngenta | I | Lambda-cyhalothrin | termite barrier | RR | 10/10/2002 | 2003 |
| Valent | I | Pyriproxyfen | Brassica leafy vegetables, cucurbit vegetables, olive | RR/OP Alt. | 3/7/2003 | 2003 |
| IR-4 | F | Cyprodinil | bushberry, caneberry, pistachio, watercress | RR | 3/13/2003 | 2003 |
| Exit Holdings | Ro | EH-2001 Rodenticide | Richardson/Wyoming ground squirrel | RR | 3/24/2003 | 2003 |
| IR-4 | H | Mesotrione | corn (pop) | RR | 3/25/2003 | 2003 |
| Dow | I | Noviflumuron | above ground bait station | RR/OP Alt. | 5/13/2003 | 2003 |
| IR-4 | I | Pyriproxyfen | avocado fruits, fig, okra,sugar apple fruits | RR/OP Alt. | 5/30/2003 | 2003 |
| Bayer | I | Clothianidin | canola, corn (seed treatments) | OP Alt. | 5/30/2003 | 2003 |
| IR-4 | I | Methoxyfenozide | cranberry, cucurbits, okra, pea (blackeyed, southern), turnip (greens) | RR/OP Alt. | 5/30/2003 | 2003 |
| IR-4 | F | Azoxystrobin | artichoke (globe), asparagus, head & stem Brassica subgroup, herbs | RR | 6/18/2003 | 2003 |
| Novartis | I | Emamectin benzoate | cotton, fruiting vegetables, tobacco | OP Alt. | 7/1/2003 | 2003 |
| IR-4 | I | Buprofezin | bean (succ.), lychee fruits, pistachio | RR/OP Alt. | 7/15/2003 | 2003 |
| BASF | F | Boscalid (BAS 510) | berries, bulb vegetables, canola, fruiting vegetables, grape, legume vegetables, lettuce (head, leaf), peanut, root vegetables (except sugar beet, garden beet, radish, turnip), stone fruit, strawberry, tree nuts, tuberous & corm vegetables, turf | RR | 7/21/2003 | 2003 |
| Novartis | I | Thiamethoxam | ornamentals | OP Alt. | 7/30/2003 | 2003 |
| IR-4 | F | Trifloxystrobin | leaf petioles; root vegetables (except sugar beet) subgroup, except radish | RR | 9/10/2003 | 2003 |
| IR-4 | I | Thiamethoxam | beans, succulent (seed); stone fruit; sunflower (seed) | OP Alt | 9/17/2003 | 2003 |
| Syngenta | H | Butafenacil | cotton | OP Alt. | 9/19/2003 | 2003 |
| IR-4 | F | Cyprodinil | Brassica leafy vegetables, carrot, herbs, lychee fruits | RR | 9/19/2003 | 2003 |
| FMC/ISK Biosciences | I | Flonicamid | ornamentals (greenhouse) | OP Alt. | 9/26/2003 | 2003 |
| Tomen Agro | I | Acequinocyl | ornamentals (greenhouse) | RR | 9/26/2003 | 2003 |
| IR-4 | I | Bifenazate | cucurbits, fruiting vegetables, mint, pistachio, tomato (greenhouse), tree nuts | RR | 9/26/2003 | 2003 |
| IR-4 | F | Fenhexamid | cucumber (greenhouse), fruiting vegetables (except non-bell pepper), kiwifruit, leafy green subgroup (except spinach), stone fruit | RR | 9/26/2003 | 2003 |
| Valent | I | Etoxazole | cotton, pome fruit, strawberry | RR | 9/26/2003 | 2003 |
| Dow | F | Quinoxyfen | grape, hops | RR | 9/29/2003 | 2003 |
| IR-4 | F | Quinoxyfen | cherry | RR | 9/29/2003 | 2003 |
| Bayer | H | Glufosinate-ammonium | rice | RR | 9/30/2003 | 2003 |
| Dow Agro | H | Fluroxypyr | corn (field, sweet) | RR | 12/31/2003 | 2004 |
| Bayer | H | Mesosulfuron-methyl | wheat | RR | 3/31/2004 | 2004 |
| Syngenta | I | Gamma-cyhalothrin (Isomer of lambda-cyhalothrin) | alfalfa, Brassica head & stem subgroup, canola, corn (field, sweet), cotton, fruiting vegetables, garlic, legume vegetables (edible-podded) subgroup, lettuce (head, leaf), tree nuts, onion (dry bulb), pea and bean dry shelled (except soybean) subgroup, pea and bean succulent shelled subgroup, peanut, pome fruit, rice, sorghum, soybean, stone fruit, sugarcane, sunflower, wheat | OP Alt. | 4/14/2004 | 2004 |
| Makhteshim-Agan | I | Novaluron | cotton, pome fruit | OP Alt | 6/2/2004 | 2004 |
| Nichino | I | Fenpyroximate | cotton, grape, pome fruit | RR | 6/10/2004 | 2004 |
| Exponent/Agro Kanesho | I | Acequinocyl | strawberry | RR | 7/21/2004 | 2004 |
| Arvesta | I | Acequinocyl | almond, citrus, pome fruit, field ornamentals | RR | 7/21/2004 | 2004 |
| Syngenta | I | Lufenuron | termite bait station | RR | 8/5/2004 | 2004 |
| DuPont | I | Indoxacarb | fire ant bait | RR/OP Alt. | 8/18/2004 | 2004 |
| Janssen/Bayer | F | Pyrimethanil | almond, grape, onion (dry bulb, green), pome fruit, stone fruit, strawberry, tomato, tuberous & corm vegetables | RR | 8/26/2004 | 2004 |
| Mitsui | I | Dinotefuran | leafy vegetables | RR/OP Alt. | 9/17/2004 | 2004 |
| Dow Agro | H | Penoxsulam | rice | RR | 9/24/2004 | 2004 |
| Dow Agro | I | Tebufenozide | citrus | RR | 9/24/2004 | 2004 |
| IR-4 | I | Tebufenozide | grape, tuberous & corm vegetables | RR | 9/24/2004 | 2004 |
| Bayer | F | Fenamidone | cucurbit vegetables, onion (dry bulb, green), potato, tomato | RR | 9/29/2004 | 2004 |
| ISK Biosciences | F | Cyazofamid | cucurbit vegetables, potato, tomato | RR | 9/30/2004 | 2004 |
| Valent | H | Bispyribac-sodium | turf | RR | 9/30/2004 | 2004 |
| Bayer | I | Deltamethrin | corn (field), cucurbit vegetables, fruiting vegetables, onion (dry bulb, green), pome fruit, root & tuber vegetables, sorghum, tree nuts | OP Alt. | 9/30/2004 | 2004 |
| Bayer | F | Fenamidone | ornamentals | RR | 10/19/2004 | 2005 |
| Farnam | I | Diflubenzuron | Horse oral larvicide feed-through treatment | RR | 11/19/2004 | 2005 |
| Mitsui | I | Dinotefuran | public health use | RR/OP Alt. | 11/22/2004 | 2005 |
| Arvesta | I | Clothianidin | turf, ornamentals | OP Alt. | 11/30/2004 | 2005 |
| IR-4 | I | Thiamethoxam | mint | OP Alt. | 12/22/2004 | 2005 |
| Arvesta | I | Clothianidin | pome fruit, tobacco | OP Alt. | 2/23/2005 | 2005 |
| Makhteshim | I | Clofentezine | grape | RR | 3/9/2005 | 2005 |
| Mitsui | I | Dinotefuran | cotton, brassica head & stem subgroup, cucurbit vegetables,fruiting vegetables, grape, potato | RR/OP Alt. | 3/23/2005 | 2005 |
| Syngenta | H | Mesotrione | corn (sweet) | RR | 3/23/2005 | 2005 |
| Nichino | I | Buprofezin | avocado, guava, peach, pome fruit, sugar apple | RR/OP Alt | 4/8/2005 | 2005 |
| Nippon Soda | I | Acetamiprid | potato | RR/OP Alt. | 4/25/2005 | 2005 |
| Syngenta | I | Spiromesifen | Brassica leafy vegetables, corn (field), cotton, cucurbits, fruiting vegetables, leafy greens, ornamentals, strawberry, tuberous & corm vegetables (retroactive classification, 11/28/06) | RR | 5/3/2005 | 2005 |
| IR-4 | I | Pymetrozine | asparagus | OP Alt. | 7/27/2005 | 2005 |
| Valent | I | Etoxazole | grape, tree nuts | RR/OP Alt. | 7/28/2005 | 2005 |
| Syngenta | H | Pinoxaden | barley, wheat | RR | 7/27/2005 | 2005 |
| Dow Agro | H | Aminopyralid | range & pasture lands, rights of way, roadsides, industrial vegetation management | RR | 8/10/2005 | 2005 |
| ISK Biosciences | I | Flonicamid | cotton, cucurbit vegetables, fruiting vegetables, pome fruit, potato, stone fruit, nursery & landscape ornamentals | OP Alt. | 8/31/2005 | 2005 |
| IR-4 | F | Boscalid | celery, spinach | RR | 2/8/2006 | 2006 |
| Valent | H | Flumiclorac-pentyl | cotton defoliant use | RR/OP Alt. | 3/8/2006 | 2006 |
| IR-4 | I | Spinosad | alfalfa, fruit fly bait, mint, onion (green) | RR | 3/8/2006 | 2006 |
| IR-4 | F | Fenhexamid | ginseng, pear | RR | 3/29/2006 | 2006 |
| ISK BioSciences | I | Flonicamid | head & stem Brassica | OP Alt. | 3/29/2006 | 2006 |
| IR-4 | F | Trifloxystrobin | barley, oats | RR | 3/29/2006 | 2006 |
| IR-4 | F | Azoxystrobin | herbs, spices, safflower, sunflower | RR | 5/3/2006 | 2006 |
| Dow Agro | I | Methoxyfenozide | soybean | RR/OP Alt. | 6/7/2006 | 2006 |
| IR-4 | F | Fenhexamid | cilantro, pepper (non-bell), pomegranate | RR | 8/2/2006 | 2006 |
| IR-4 | I | Fenpyroximate | citrus, hops, mint, pistachio, tree nuts | RR | 8/23/2006 | 2006 |
| IR-4 | F | Quinoxyfen | lettuce (head, leaf), melons, pepper (bell, non-bell), strawberry | RR | 8/25/2006 | 2006 |
| IR-4/Uniroyal | I | Bifenazate | stone fruit, edible-podded pea, tuberous & corm vegetables | RR/OP Alt. | 8/30/2006 | 2006 |
| KI-Chemical | H | Fluthiacet-methyl | cotton | OP Alt. | 12/27/2006 | 2007 |
| Syngenta | I | Spiromesifen | tomato (greenhouse) | RR | 1/31/2007 | 2007 |
| ISK BioSciences | F | Flazasulfuron | turf | RR | 5/14/2007 | 2007 |
| Dow Agro | H | Penoxsulam | turf | RR | 6/13/2007 | 2007 |
| DuPont | I | Indoxacarb | grape | RR | 7/6/2007 | 2007 |
| Dow Agro | H | Penoxsulam | aquatic use | RR | 7/17/2007 | 2007 |
| Dow Agro | I | Spinosad | mosquito larvicide use | RR | 8/29/2007 | 2007 |
| Dow Agro | I | Spinetoram | acerola, amaranth, pome fruit, stone fruit, artichoke (globe), asparagus, atemoya, avocado, banana, biribi; head & stem Brassica; Brassica leafy greens; bulb vegetables; bushberry; caneberry; canistel; cereal grains (ex. rice, sorghum, millet); cherimoya; citrus; corn (sweet); cotton; cranberry; cucurbit vegetables; custard apple; feijoa; fig; foliage of legume vegetables; fruiting vegetables; grape; guava; herbs (dried, fresh); ilama; jaboticaba; juneberry; leafy vegetables; leaves of root & tuber vegetables; legume vegetables, edible-podded; lingonberry; longan; lychee; mango; mint; okra; papaya; passion fruit; pea & bean, dried, shelled (ex. soybean); pea & bean, succulent shelled; peanut; pistachio; pulusan; rambutan; root & tuber vegetables; salal; sapodilla; sapote (black); sapote (mamey); sapote (white); sorghum; soursop; spanish lime; star apple; star fruit; strawberry; sugar apple; ti leaves; tree nuts; watercress; wax jambu | RR | 9/28/2007 | 2007 |
| Syngenta | H | Mesotrione | turf (sod farm, golf courses) | RR | 12/12/2007 | 2008 |
| Syngenta | F | Mandipropamid | Brassica Leafy Vegetables, Bulb Vegetables, Cucurbit Vegetables, Fruiting Vegetables, Grape, Tuberous & Corm Vegetables, Leafy Vegetables | RR | 1/9/2008 | 2008 |
| IR-4 | I | Etoxazole | Cherry, Melon (subgroup 9A), Hops | RR | 1/10/2008 | 2008 |
| IR-4 | H | Mesotrione | Berry, Cranberry, Flax | RR | 1/16/2008 | 2008 |
| IR-4 | I | Methoxyfenozide | Avocado; Bean (dry, seed); Bushberry; Grass, Forage, Fodder & Hay; Guava; Non-Grass Animal Feeds; Onion (green); Peanut; Tuberous & Corm Vegetables | RR | 2/27/2008 | 2008 |
| IR-4 | I | Spinosad | Pineapple, Spices (ex. black pepper) | RR | 2/27/2008 | 2008 |
| IR-4 | I | Spiromesifen | Bean (dry, edible-podded, succulent) | RR | 3/14/2008 | 2008 |
| Syngenta | H | Mesotrione | Asparagus, Grass (grown for seed), Oat, Okra, Rhubarb, Sorghum, Sugarcane | RR | 3/17/2008 | 2008 |
| DuPont | I | Chlorantraniliprole | Cotton, Grape, Pome Fruit, Potato, Stone Fruit, Brassica Leafy Vegetables, Cucurbit Vegetables, Fruiting Vegetables, Leafy Vegetables, Turf, Ornamentals | RR | 4/25/2008 | 2008 |
| Bayer | I | Spirotetramat | Almond, Brassica Head & Stem Vegetables, Brassica Leafy Greens, Citrus, Cucurbits, Fruiting Vegetables, Grape, Hops, Leafy Vegetables, Onion (bulb), Pome Fruit, Stone Fruit, Strawberry, Tree Nuts, Tuberous & Corm Vegetables | RR | 6/30/2008 | 2008 |
| Wellmark | I | Etofenprox | Mosquito Adulticide Use | RR | 8/15/2008 | 2008 |
| Mitsui/Landis | I | Etofenprox | Rice | RR | 12/8/2008 | 2009 |
| Syngenta | H | Mesotrione | Turf (commercial, residential) | RR | 2/19/2009 | 2009 |
| Bayer, IR-4 | I | Spiromesifen | Corn (pop, sweet), Low-growing berry group | RR | 4/22/2009 | 2009 |
| Dow Agro | H | Penoxsulam | Grape, Tree Nuts | RR | 4/24/2009 | 2009 |
| DuPont | I | Chlorantraniliprole | Tree Nuts, Pistachio | RR | 6/16/2009 | 2009 |
| IR-4 | I | Etoxazole | Cucumber, Mint, Plum, Stone Fruit (ex. plum), Tomato (GH) | RR | 7/14/2009 | 2009 |
| IR-4 | F | Cyazofamid | Fruiting Vegetables, Grape (regional tolerance), Okra | RR | 7/29/2009 | 2009 |
| IR-4 | I | Spinetoram | Date, Hops, Pineapple, Pomegranate, Spice (ex. black pepper) | RR | 8/13/2009 | 2009 |
| BASF | H | Saflufenacil | Cereal Grains; Citrus; Cotton; Foliage of Legume Vegetables; Forage, Fodder, & Straw of Cereal Grains; Grape; Legume Vegetables; Pome Fruit; Stone Fruit; Sunflower; Tree Nuts | RR | 9/3/2009 | 2009 |
| IR-4 | I | Methoxyfenozide | Citrus, Corn (pop), Pea (dry seed), Pomegranate | RR | 9/18/2009 | 2009 |
| IR-4 | I | Pyriproxyfen | Artichoke (globe), Asparagus, Foliage of Legume Vegetables, Leafy Vegetables, Leaves of Root & Tuber Vegetables, Small Vine Climbing Fruits (ex. grape), Watercress | RR | 11/5/2009 | 2010 |
| IR-4 | I | Dinotefuran | Brassica leafy greens, Turnip (greens) | RR | 12/23/2009 | 2010 |
| IR-4 | I | Endothall | Irrigation Canal Use | RR | 12/30/2009 | 2010 |
| DuPont | I | Chlorantraniliprole | Artichoke, Asparagus, Caneberry, Cacao, Citrus, Coffee, Corn (field, sweet, pop), Fig; Forage, Fodder & Straw of Cereal Grains; Grass Forage, Fodder, & Hay; Herbs & Spices; Hops; Legume Vegetables (ex. soybean); Mint; Non-grass Animal Feeds; Oilseed Crops; Okra; Olive; Peanut; Persimmon; Pomegranate; Prickly Pear Cactus; Rice; Small Vine-climbing Fruits; Strawberry; Sugar, cane; Tea; Tobacco; Tropical Fruits; Tuberous & Corm Vegetables | RR | 2/19/2010 | 2010 |
| DuPont | I | Chlorantraniliprole | Termiticide Use | RR | 5/20/2010 | 2010 |
| Nichino | I | Tolfenpyrad | Ornamentals (Greenhouse) | RR | 7/28/2010 | 2010 |
| IR-4 | F | Cyazofamid | Brassica Leafy Vegetables, Hops, Spinach, Turnip (greens) | RR | 8/13/2010 | 2010 |
| Bayer | I | Spiromesifen | Pea, dry | RR | 9/1/2010 | 2010 |
| Bayer | I | Spirotetramat | Cotton, Legume Vegetables, Tropical Fruits | RR | 5/6/2011 | 2011 |
| DuPont | I | Chlorantraniliprole | Bushberry, Cucurbit Vegetables, Fruiting Vegetables Okra, Onion, bulb, Root & Tuber Vegetables, Sugar beet, Tea | RR | 7/15/2011 | 2011 |
| Landis | I | Novaluron | Termite Bait Station Use | RR | 2/8/2012 | 2012 |
| Mitsui/Landis | F | Penthiopyrad | Alfalfa, Bulb Vegetables, Brassica Leafy Vegetables, Canola, Cereal Grains, Corn (field, pop, sweet), Cotton, Cucurbits, Fruiting Vegetables, Leafy Vegetables, Legumes, Low-growing Berry, Peanut, Pome Fruit, Root & Tuber Vegetables, Soybean, Stone Fruit, Sunflower, Tree Nuts, Turf, Ornamentals | RR | 2/29/2012 | 2012 |
| BASF | F | Ametoctradin | Brassica Leafy Vegetables, Bulb Vegetables, Cucurbits, Fruiting Vegetables, Grape, Hops, Leafy Vegetables, Tuberous & Corm Vegetables, Turf (golf courses), Ornamentals, Residential/ Commercial Landscapes | RR | 5/17/2012 | 2012 |
| IR-4 | I | Acetamiprid | Asparagus, Brassica Leafy Greens, Citrus, Fruiting Vegetables, Pome Fruit, Turnip (greens) | RR | 8/2/2012 | 2012 |
| IR-4 | F | Azoxystrobin | Berry & Small Fruits (13-07A,B,F,G), Bulb Vegetables, Citrus, Dragon Fruit, Fruiting Vegetables, Oilseeds, Tuberous & Corm Vegetables, Wasabi | RR | 8/22/2012 | 2012 |
| DuPont | I | Chlorantraniliprole | Foliage of Legume Vegetables, Soybean, Oilseeds | RR | 9/21/2012 | 2012 |
| Mitsui | I | Dinotefuran | Rice | RR | 10/26/2012 | 2013 |
| IR-4 | I | Flonicamid | Cucumber (GH), Low-growing Berry, Rapeseed (20A) | RR | 11/14/2012 | 2013 |
| IR-4 | I | Pyriproxyfen | Herbs | RR | 12/12/2012 | 2013 |
| Mitsui | I | Dinotefuran | Food Handling Establishments | RR | 4/12/2013 | 2013 |
| IR-4 | I | Acetamiprid | Corn, sweet | RR | 6/20/2013 | 2013 |
| IR-4 | I | Etofenprox | Mosquito Adulticide Use (removing crop restriction) | RR | 11/25/2013 | 2014 |
| DuPont | I | Cyantraniliprole | Brassica leafy vegetables, bulb vegetables, bushberries, citrus, cotton, cucurbit vegetables, fruiting vegetables, leafy vegetables, oil seeds, pome fruit, stone fruit, tree nuts, tuberous & corm vegetables, fly bait use, turf, ornamentals (greenhouse and nursery), and indoor and outdoor commercial and residential use sites to control public health pests | RR | 1/24/2014 | 2014 |
| DuPont | I | Chlorantraniliprole | Peanut | RR | 2/7/2014 | 2014 |
| Bayer CropScience | I | Clothianidin | Indoor cockroach gel bait | RR | 4/7/2014 | 2014 |
| DuPont Crop Protection | F | Oxathiapiprolin | Brassica leafy vegetables, cucurbit vegetables, fruiting vegetables, leafy vegetables, and potatoes. | RR | 8/31/2015 | 2015 |
| Syngenta | F | Oxathiapiprolin | ornamentals | RR | 8/31/2015 | 2015 |
| Bayer CropScience | I | Flupyradifurone | citrus, cotton, cucurbit vegetables, fruiting vegetables, pome fruit, Brassica leafy vegetables, leafy (non-Brassica) vegetables, root and tuber vegetables, and legume vegetables | RR | 1/15/2015 | 2015 |
| Bayer Environment Science | I | Deltamethrin | All crop mosquito adulticide | RR | 3/25/2015 | 2015 |
| IR-4 / ISK Biosciences Corporation | F | Cyazofamid | Herb (19A); Pepper (Greenhouse soil drench); Tomato (Greenhouse foliar) | RR | 1/21/2016 | 2016 |
| Bayer CropScience | I | Spirotetramat | Sugar Beets | RR | 11/15/2016 | 2017 |
| IR-4 | I | Spirotetramat | Carrots | RR | 11/15/2016 | 2017 |
| IR-4 | I | Etofenprox | Mushrooms | RR | 11/15/2016 | 2017 |
| Syngenta | F | Oxathiapiprolin | Sunflower (seed treatment), Citrus and Potato (soil use) | RR | 11/14/2016 | 2016 |
| IR-4 | F | Oxathiapiprolin | Caneberry, Basil, and Mustard Greens | RR | 11/14/2016 | 2016 |
| DuPont Crop Protection | F | Oxathiapiprolin | Sunflower (seed treatment) and Soybean (seed treatment) | RR | 11/14/2016 | 2016 |
| IR-4 | I | Acequinocyl | Avocado, Dried Shelled Beans, and Summer Squash | RR | 9/13/2016 | 2016 |
| IR-4 | I | Flonicamid | Vegetable, Legume, Crop Group 6, Except Soybean and Greenhouse Grown Peppers | RR | 9/13/2016 | 2016 |
| Valent U.S.A. Corporation | I | Etoxazole | Soybean | RR | 9/13/2016 |
*In some instances in the table, the date listed might actually refer to the Federal Register tolerance publication date.