Chemicals Determined Not Likely to Present an Unreasonable Risk Following Pre-Manufacture Notification Review

This page describes the chemical substances EPA has determined are “not likely to present an unreasonable risk” following review of pre-manufacture notifications under section 5 of TSCA, as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, P.L. 114-182.

Note: For these “not likely to present an unreasonable risk” cases,” PMN submitters may commence manufacture upon notification by EPA, notwithstanding any remaining portion of the applicable review period, in accordance with section 5(g) of TSCA, as amended.

Certain of EPA’s determinations that a chemical is not likely to present unreasonable risk are based upon both the Agency’s risk assessment for the chemical substance under intended conditions of use described in the PMN and the issuance of a proposed SNUR to address certain reasonably foreseen uses. Conditions of use that fall under the restrictions of the proposed SNUR are not likely to present unreasonable risk of injury to health or the environment because (1) those conditions of use are not likely to be commenced during the pendency of proposed SNUR and (2) upon finalization of the SNUR those conditions of use would be prohibited unless and until EPA makes an affirmative determination that the significant new use is not likely to present an unreasonable risk or takes appropriate action under section 5(e) or 5(f). The links to the terms of these proposed SNURs are provided below along with the determination documents.

View the interim status of Section 5 pre-manufacture notices reviewed under TSCA.