Substitutes in Household Refrigerators and Freezers
You will need Adobe Reader to view some of the files on this page. See EPA’s About PDF page to learn more. Substitutes are reviewed on the basis of environmental and health risks, including factors such as ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptableThis designation means that a substitute may be used, without restriction, to replace the relevant ODS within the end-use specified. For example, HCFC-22 is an acceptable substitute for R-502 in industrial process refrigeration. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. and unacceptableThis designation means that it is illegal to use a product as a substitute for an ODS in a specific end-use. For example, HCFC-141b is an unacceptable substitute for CFC-11 in building chillers. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. substitutes are updated several times each year. The list of substitutes is shown below.
Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.
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| Substitute | Trade Name(s) | Retrofit/New | ODPA number that refers to the amount of ozone depletion caused by a substance. The ODP is the ratio of the impact on ozone of a chemical compared to the impact of a similar mass of CFC-11. Thus, the ODP of CFC-11 is defined to be 1.0. Other CFCs and HCFCs have ODPs that range from 0.01 to 1.0. The halons have ODPs ranging up to 10. Carbon tetrachloride has an ODP of 1.2, and methyl chloroform's ODP is 0.11. HFCs have zero ODP because they do not contain chlorine. A table of all ozone-depleting substances (https://www3.epa.gov/ozone/science/ods/index.html) shows their ODPs, GWPs, and CAS numbers. | GWPThe index used to translate the level of emissions of various gases into a common measure in order to compare the relative radiative forcing of different gases without directly calculating the changes in atmospheric concentrations. GWPs are calculated as the ratio of the radiative forcing that would result from the emissions of one kilogram of a greenhouse gas to that from the emission of one kilogram of carbon dioxide over a period of time (usually 100 years). Gases involved in complex atmospheric chemical processes have not been assigned GWPs. See lifetime. | ASHRAEASHRAE is an international organization that establishes standards for the uniform testing and rating of heating, ventilation, air conditioning, and refrigeration equipment. It also conducts related research, disseminates publications, and provides continuing education to its members. Designation (Safety Classification) |
SNAP Listing Date | Listing Status |
| Ammonia Absorption | R/N | 0 | 0 | B2 | July 28, 1995; September 5, 1996 |
Acceptable | |
| FOR12A | FOR12A | R/N | 0 | 1,100 | A1 | December 18, 2000; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| FOR12B | FOR12B | R/N | 0 | 1,000 | A1 | December 18, 2000; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| RB-276 | Free Zone, HCFC Blend Delta | R/N | 0.013 | 1,592 | A1 | September 5, 1996 | Acceptable |
| Freeze 12 | Freeze 12 | R/N | 0.013 | 1,606 | A1 | September 5, 1996 | Acceptable |
| R-416A | FRIGC FR-12, HCFC Blend Beta | R/N | 0.009 | 1,081 | A1 | February 8, 1996 | Acceptable |
| GHG-HP | HCFC Blend Lambda | R/N | 0.056 | 1,893 | A1 | February 8, 1996 | Acceptable |
| R-414A | GHG-X4, Autofrost, Chill-it, HCFC Blend Xi | R/N | 0.045 | 1,478 | A1 | September 5, 1996 | Acceptable |
| GHG-X5 | GHG-X5 | R/N | 0.032 | 2,377 | A1 | June 3, 1997 | Acceptable |
| HCFC-22/HCFC-142b | R/N | 0.055-0.065 | 1,810-2,310 | A1 | June 3, 1997 | Acceptable | |
| HFC-134a | R/N | 0 | 1,430 | A1 | March 18, 1994; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. | |
| HFC-152a | N | 0 | 124 | A2 | March 18, 1994 | Acceptable | |
| R-414B | Hot Shot, Kar Kool, HCFC Blend Omicron | R/N | 0.098 | 3,337 | A1 | September 5, 1996 | Acceptable |
| Ikon A | Ikon-12, Blend Zeta | N | 0 | N/A | A1 | June 19, 2000 | Acceptable |
| Ikon B | N | 0 | N/A | A1 | June 19, 2000 | Acceptable | |
| R-125/R-290/R-134a/R-600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | R/N | 0 | 2,530 | A1 | March 29, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-290 (Propane) | N | 0 | 3 | A3 | April 10, 2015; August 8, 2018 |
Acceptable with Use Conditions: See rule for detailed conditions. | |
| R-401A | SUVA MP-39 | N | 0.037 | 1,182 | A1 | January 13, 1995 | Acceptable |
| R-401B | SUVA MP-66 | N | 0.040 | 1,288 | A1 | January 13, 1995 | Acceptable |
| R-402A | HP-80 | R | 0.019 | 2,746 | A1 | August 26, 1994 | Acceptable |
| R-402B | HP-81 | R | 0.03 | 2,379 | A1 | August 26, 1994 | Acceptable |
| R-404A | SUVA HP-62 | R/N | 0 | 3,920 | A1 | March 18, 1994; January 13, 1995; December 20, 2002; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-406A | GHG-12, GHG-X3, McCool, Autofrost X3 | R | 0.057 | 1,900 | A2 | August 26, 1994 | Acceptable |
| R-407C | Suva 407C, Klea 407C | R/N | 0 | 1,770 | A1 | February 8, 1996; December 20, 2002; August 21, 2003; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-407F | Genetron Performax LT | R/N | 0 | 1,820 | A1 | October 4, 2011; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-409A | HCFC Blend Gamma | R | 0.047 | 1,558 | A1 | August 26, 1994 | Acceptable |
| R-410A | AZ-20, Suva 9100, Puron | N | 0 | 2,090 | A1 | February 8, 1996; December 20, 2002; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-410B | N | 0 | 2,230 | A1 | February 8, 1996; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. | |
| R-417A | ISCEON 59, NU-22 | R/N | 0 | 2,350 | A1 | December 6, 1999; June 16, 2010; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-420A | Choice R-420A | R/N | 0.008 | 1,536 | A1 | October 1, 2004 | Acceptable |
| R-421A | Choice R-421A | R/N | 0 | 2,630 | A1 | September 28, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-421B | Choice R-421B | R/N | 0 | 3,190 | A1 | September 28, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-422A | ISCEON 79 | R/N | 0 | 3,140 | A1 | October 1, 2004; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-422B | ICOR XAC1, NU-22B | R/N | 0 | 2,530 | A1 | March 29, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-422C | ICOR XLT1 | R/N | 0 | 3,390 | A1 | March 29, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-422D | ISCEON MO29 | R/N | 0 | 2,730 | A1 | September 28, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-424A | RS-44 | R/N | 0 | 2,440 | A1 | September 28, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-426A | RS-24 | R/N | 0 | 1,510 | A1 | September 28, 2006; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-427A | Forane 427A | R | 0 | 2,140 | A1 | January 2, 2009 | Acceptable |
| R-428A | RS-52 | R/N | 0 | 3,610 | A1 | October 4, 2007; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-434A | RS-45 | R/N | 0 | 3,250 | A1 | October 4, 2007; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-437A | KDD6, ISCEON MO49 Plus | R/N | 0 | 1,810 | A1 | January 2, 2009; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-438A | KDD5, ISCEON MO99 | R/N | 0 | 2,270 | A1 | October 4, 2007; June 16, 2010; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-441A | HCR-188C | N | 0 | <5 | A3 | December 20, 2011; August 8, 2018 |
Acceptable with Use Conditions: See rule for detailed conditions. |
| R-450A | Solstice® N-13 | R/N | 0 | 601 | A1 | October 21, 2014 | Acceptable |
| R-507, R-507A | AZ-50 | R/N | 0 | 3,990 | A1 | January 13, 1995; December 20, 2002; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| R-513A | Opteon® XP 10 | R/N | 0 | 630 | A1 | July 16, 2015 | Acceptable |
| R-600a (Isobutane) | N | 0 | 3 | A3 | December 20, 2011; August 8, 2018 |
Acceptable with Use Conditions: See rule for detailed conditions. | |
| RS-24 (2002 formulation) | R/N | 0 | 1,510 | A1 | December 20, 2002; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. | |
| RS-44 (2003 formulation) | R/N | 0 | 2,420 | A1 | August 21, 2003; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. | |
| Self-chilling cans using CO2 | N | 0 | 1 | A1 | February 24, 1998 | Acceptable | |
| SP34E | SP34E | R/N | 0 | <1,470 | A1 | December 18, 2000; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. |
| THR-01 | N | >0 | N/A | A2 | February 24, 1998 | Acceptable | |
| THR-02 | N | 0 | N/A | A1 | December 6, 1999 | Acceptable | |
| THR-03 | R/N | 0 | N/A | A1 | December 6, 1999; December 1, 2016 |
Unacceptable in new equipment, as of January 1, 2021. | |
| THR-04 | R/N | >0 | N/A | A1 | June 8, 1999 | Acceptable |